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Inside the Immune System: Anatomy, Functions, and How It Protects You

Written by Nishant Garund
Medically Reviewed by Dr.Varuni Agarwal

Dr. Varuni Agarwal is an esteemed Ayurvedic physician specializing in
diagnosing diseases through Ayurvedic dosha imbalances and providing personalized treatments. She focuses on ahara (diet) and vihara (lifestyle) to manage and heal various ailments.

Inside the Immune System: Anatomy, Functions, and How It Protects You

The human body is an amazing machine that can protect itself from a wide range of perilous intruders because of its highly developed immune system. To keep us healthy, this sophisticated framework of tissues, cells, and organs works nonstop to keep us protected against infections and illnesses. Knowing about the immune system's types, roles, structure, and mechanisms might help us better understand how our bodies protect us from harm and keep us protected from threats. We'll traverse the amazing world of the immune system in this blog, learning about its defence mechanisms and much more.

Immune System: An Overview 

According to the National Cancer Institute, the Immune System is a complicated system of tissues, organs, cells, and the fusion they produce that helps in the body’s fight against illness and infections. White Blood cells, lymph veins, and bone marrow are the body’s defence against infection. The immune system keeps a record of every microbe it has ever defeated so it can recognise and destroy the microbe quickly if it enters the body again. Anomalies of the immune system can lead to allergic diseases, immunodeficiencies and autoimmune disorders.

Types of Immune System and Immunity

There are three crucial types of immunity to consider - innate, adaptive and passive.

  • Innate immunity: Also known as natural immunity, is a kind of broad defence that all people possess from birth. For instance, the skin serves as a barrier to keep pathogens out of the body. The immune system knows when some intruders are alien and harmful. Enzymes and bodily fluids with an acidic pH are examples of chemical barriers that limit the growth of microorganisms. Natural killer (NK) cells, neutrophils, and macrophages are cellular components of innate immunity that use processes like phagocytosis—which involves engulfing and breaking down infections—and the release of toxic chemicals to identify and eliminate pathogens.
  • Adaptive immunity: Also known as active immunity, it is the immunity that we develop throughout life. When we are vaccinated against diseases or exposed to them, we build adaptive immunity. Specialised cells called lymphocytes, including B cells (B lymphocytes) and T cells (T lymphocytes). B cells create antibodies which attach to specific antigens on the pathogen, whereas T cells assist in coordinating the immune response and actively eliminate contaminated cells.
  • Passive immunity: It is temporary and is “borrowed” from another source. For instance, a baby’s temporary immunity. Antibodies in a mother’s breast milk provide temporary immunity against diseases a mother has been exposed to.

Structure of the Immune System

The immune system is a network of complex tissues and cells. It organises immunological reactions. Below are few of the important ones: 

Tissues and Organs: 

  • Primary Lymphoid Organs: Thymus and bone marrow are the sites of the production and maturation of immune cells such as Lymphocytes.
  • Secondary Lymphoid Organs: Tonsils, spleen, lymph nodes, and mucosa-associated lymphoid tissues (MALT) are some examples of SLOs. These organs function as sites for immune cell contact, antigen presentation and the start of immunological responses.

Cells:

  • Phagocytes:  Pathogens are ingested and digested by macrophages, neutrophils, and dendritic cells, which then transmit their antigens to trigger the immune cells.
  • Lymphocytes: T cells coordinate immune responses, including cytotoxic T cell's destruction of infected cells and their assistance in the activation of other immune helper T cells. B cells generate antibodies that identify and neutralise particular antigens.

What does the immune system do? 

The immune system performs several crucial functions to protect the body. Let's know what are those below.

  • Pathogen Identification and Elimination: Immune cells utilise specialised receptor, Pattern Recognition Receptors (PRRs) to identify shared molecular patterns across different pathogens. The first set of immunological reactions meant to eliminate the invaders.
  • Neutralization of Toxin: Toxin secreted by bacteria or viruses can be neutralised by antibodies made by B cells, stopping them from damaging the body’s tissues and cells. 
  • Replacing Dead cells and tissues: The immune system aids in the removal of dead cells from the body, encouraging tissue regeneration and repair.
  • Immunological Memory: The immune system’s capacity to recall preceding infections is an amazing feature. Memory cells - long-lived B and T cells produced during the first infection or vaccination, allow more potent defence. Discovery of vaccination and long-term protection against diseases polio, and influenza in this phenomena.   
immune system fight against the pathogens

How the Immune system protect the body from diseases?

  • Preventing Infections: To prevent pathogen, the immune system uses membranes such as skin and mucous membranes as barriers.
  • Fighting Infections: The immune system uses phagocytosis and the generation of antibodies, among other methods, to recognise and eliminate infections.
  • Long-term Protection: Vaccines develop immunity by imitating illnesses and teaching the immune system to identify and fight germs without spreading illness. 

Healthy Lifestyle for A Healthy Immune System: Here’s What You Should Do

  • Eating a balanced diet: Including fruits, vegetables, and whole grains provides essential nutrients.
  • Stay active: Regular physical activity such as yoga boosts your health and overall immunity.
  • Get enough sleep: The eight hour sleep rule must be followed with content to see great results on overall health.
  • Stay hydrated: Drink plenty of water to flush out excess toxins from the body.
eat healthy for a strong immune system

Conclusion

The immune system is a phenomenon of biological engineering, crucial to survival. We can better appreciate its ability to protect us from diseases if we know its composition, roles, and working mechanism. Keeping a healthy lifestyle helps our immune system work at its best, protecting us. 

Frequently asked questions

Q. What is the Immune system's organ and function?

The immune system is made up of the spleen, lymph nodes, bone marrow, and thymus. The bone marrow produces white blood cells, the spleen filters blood and fights infections, the lymph nodes capture and eliminate germs, and the thymus helps in the production of T cells. When together, they help the body fight against infections and illnesses by recognising and eliminating viruses and bacteria.

Q. What is the main function of the immune system?

 Protecting the body from bacteria and viruses is the main duty of the immune system. It operates by locating these trespassers, confronting them, and getting rid of them. The parts of the immune system work together to find, destroy, and hold onto these invaders so the body is ready to fight them off if they recur.

Q. How does the immune system protect the body from disease?

The immune system defends the body against illness by identifying and eliminating dangerous organisms such as bacteria and viruses. It accomplishes this by utilising a network of specialised proteins and cells to recognise, locate, and destroy these intruders. Crucially, it retains the memory of previous infections, enabling a quicker and more efficient reaction if the same virus tries to re-invade. Through the prevention of infections and preservation of homeostasis, this intricate defence mechanism keeps the body safe from attacks on its tissues.